It’s easier to hit the VFR wall on larger nozzles due to the hotend would be hard to keep up with the temperature, and you’re essentially getting 3.375 times more plastic (0.4->0.6 diameter, so 1.5x1.5x1.5 in xyz) to extrude. So yes, it’s much more challenging on large nozzles. But still, HF nozzles are beneficial even on 0.4mm, you get more than just speed changes: you get stronger parts, improved layer adhesions, better printability on low layerheights (like 0.08mm), less extrusion artefacts, lower nozzle backpressure…
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