Is calibration necessary for every new spool?

Well, I’ve just pulled myself out from the YouTube rabbit hole. It could have been hours but feels like days!

I’ve seen retraction tests, VRF tests, heat tower tests that require modifying gcode. Can anyone recommend a good set of “do these four calibration tests”. I’m no where near ready to pull the engine, I’ve just figured out how to open the hood!

For context, I just tried my first PETG print and holy ■■■■; 5 minutes in I had a complete spaghetti mess.