Not necessarily. Filament manufacturers use special ovens to dry filament. They don’t explain that their drying at 8 hours and 65C works in their special ovens but is only a guideline with consumer filament dryers.
If you want to know if your drying is effective, do the Ziplock bag test I described above with a spool fresh out of your filament dryer. It’s the easiest way to know if your drying is effective and not have to guess.
High ambient humidity can stop drying in its tracks. If you aren’t monitoring humidity during the dry, you may be drying and you may not. Since you are seeing print defects, I’m guessing you aren’t drying as effectively as you may think you are.