I have a spool of PolyDissolve S1 here and I have plans to test it when I get to it.
I have kinda same goals as you - printing functional parts in-doors and do care about my health. I just haven’t gotten into supports yet, because I am still working on optimising PETG on its own.
Have you looked into other filaments where you could have used Support G with?
PAHT-CF looks promising. Toxicity of filaments Perhaps you have something to add? Maybe PAHT-CF not being safe printing indoors?
I plan to start with PA after I assemble bentobox.