Filament calibration for different nozzle sizes?

I just finished calibrating (Orca Slicer) a 3rd party PETG filament using 0.4 harden nozzle. It seems to be working, the filament was printing like ■■■■ using generic PETG profile.

Do I need to repeat the calibration process for each nozzle size? or software is smart enough to calculate it for us? Thanks.