I have quite a few projects where there may be multiple plates with very specific orientation and placement of parts.
The issue I am having is that quite often the parts will not be where I placed them upon opening the file to print the project again. This is repeatable too - I can redo the tedious task of repositioning the parts, SAVE, then reopen and they are right back to where I didn’t place them.
Just like the AMS filament selection issue I posted, failing to catch this has cost me a fair amount of time and filament and a lot of frustration.