Here’s my five Cents worth…
If there is a Studio update it DOES help to uninstall and clean up before installing the new version.
Somehow Studio loves to create a mess with a normal update.
If there is a new firmware it is a must to do the full printer calibration as only too often those values found the first time around get lost during the firmware update.
Updated Studio, the printer or both and suddenly there no connection possible ?
Say thank you to Bambu 
The BambuStudio.conf file holds the access code for the printer and your filament allocations.
For some reason the access code is now added to the config file towards the end of the file!
During an update the config file is preserved and you can end up with two different codes in it.
If in doubt use Notepad++ to check and correct this.
Quite often the only way to regain a working connection is to go through the cloud mode using Handy.
The 1.0.7 firmware seems to have broken the access code binding through Studio.
You can enter the IP and code in Lan Only mode but the connection and binding keeps failing.
Once printer and Studio are connected through the cloud you can bind the printer using the pin code but in the conf file you will then find the correct ACCESS code - no clue how or why Bambu does this…
If you ask me it is just another addition to the list of controls.
Making sure the printer, handy and Studio are doing the whole cloud thing so that ‘we can authenticate our products and accounts’ to Bambu…